Introduction: During the development, 7th cervical intersegmental artery would lead to the axis artery. Axis artery is the major artery from which all other branches of the upper limb arteries arise. Materials and Methods: In the present case, variation in the branching pattern of the axis artery of upper limb was observed in an adult male cadaver. Results: There was an additional branch arising from the brachial artery and it was running in the forearm. As usual, the brachial artery bifurcated into ulnar and radial arteries. Conclusions: The knowledge of variations reported here is important to the operating surgeons and radiologists.