Human brain slices were used which were stained and embedded in resin for retention of parts of the central nervous system (CNS). The application of the technique of embedding in resin prevents wear due to constant handling practical classes and research. Human brain, fixed in 20% formaldehyde, were cut into coronal sections and stained by the Mainland method. After staining, sections were dehydrated and accommodated in a pan of acetate and immersed in a liquid crystal resin solution. After catalysis the block was removed from the mold and its surface was planned and standardized using sandpaper in increasing weights. We observed brain sections stained by the Mainland allowing differentiation between gray and white matter, beyond the view of the basal ganglia and surrounding structures. Furthermore, the resin inclusion allowed the visualization through transparency, no wear of the cuts, increasing the life of the anatomical parts. This feature provides anatomy laboratories means for protection of parts against air, moisture and handling damage, further promoting the protection of those who use the parts, since the damages caused by the chemical formaldehyde used for fixation and preservation of anatomical specimens are known.