Cystic artery is usually a branch of right hepatic artery given in the Calot’s triangle. Variations in the origin of cystic artery have been previously reported. The present case report describes the origin of cystic artery from the common hepatic artery taking an unusual course, which was detected during routine dissection. These kinds of variations are expected to arise if anything goes wrong during the embryological development of biliary vasculature. An attempt has been made to discuss the surgical and embryological relevance of the reported anomaly.