Craniofacial bone variations, considered to be radiological landmarks, have been studied since the beginning of the century using dried skulls and cadavers. These pitfalls are important bone landmarks used in the planning and execution of anesthetic and surgical procedures. The present study analyzed craniofacial bone variations in dried skulls in terms of gender and laterality. Supraorbital foramen (SOF), mastoid foramen (MF), parietal foramen (PF), accessory oval foramen (aOF), anterior ethmoidal foramen (AEF), intermediate ethmoidal foramen (iEF), posterior ethmoidal foramen (PEF), precondylar tubercle (PCT), metopism and sutural bones were assessed in male (n=20) and female (n=11) dried skulls by direct observation and using a Mitutoyo caliper. No statistically significant differences were observed between genders as to SOF distances to the medial nasal prominence and to superior orbital ridge, in both sides of skulls. The same was observed for distances between FP and sagittal line and between FP and lambdoid suture. No multiple foramina were detected. aOF was observed in 80.96% of skulls. Right aEF, iEF and PEF prevailed in female skulls. PCT were seen in 35.5% of female skulls and in 64.5% of male skulls. MF occurrence was higher in right male skulls, and multiple foramina were present in 60% of male skulls (both sides), and in 36.4% of female skulls (both sides). Only one skull presented sutural bone. No metopism was observed. The identification and recording of craniofacial variations is important in the preparation of anesthetic blocks in surgical procedures and in the evaluation of regional neurovascular anatomy, to avoid misinterpretations in planning. This study confirms the existence of significant morphological variations in terms of gender and side in a given population.