The role of neurosecretion in the annual reproductive cycle of male scorpion was studied by taking monthly samples around 15th of every month and the role in courtship-mating was studied from the samples taken during courtship, immediately after mating, at 6 hours, 12 hours, 24 hours after mating and 4th and 7th days of post-mating period. From the observations, it is inferred that the neurosecretory cells of groups 2, B and 3 to 9 take part in triggering the testicular maturation. Sets I, III and group C cells possibly play a role in the gradual maturation process of the testes while set II cells indicate their involvement in the mature stage. The increase in the synthetic activity of protocerebral neurosecretory cells (NS cells) manifested by the histological appearance of phloxinophilic material inside protocerebral vacuolar spaces in the spent and slow-maturing stages is considered to suggest the involvement of these protocerebral NS cells in testicular maturation. The release of phloxinophilic secretary globules from group 3 cells and phloxinophilic accumulations near groups 5 and 6 throughout the annual cycle was inferred to signify their possible involvement in all the phases of testicular activity and/or activities supporting extra-testicular events contributing to the overall reproductive processes. The results indicated the possible involvement of set I, groups 4 and 6 in the courtship of the male scorpion. Sets II, III, group 2 of brain and all NS cell groups of sub-oesophageal anglion except groups 4 and 6 were suggested to be possibly involved in both courtship and mating.